Changes between Version 16 and Version 17 of UseCases

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Timestamp:
2010/02/09 16:41:28 (7 years ago)
Author:
gordonp
Comment:

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  • UseCases

    v16 v17  
    5454    * The query in Prolog would be something like (simplified so it's depending only on known protein domains, whereas in the publication we built our own domain models): 
    5555 
    56       probableNovelInteractors(HumanGene1, HumanGene2) :- hasHomolog(HumanGene1, YeastGene1), hasInteractorFromDB(YeastGene1, YeastGene2), hasHomolog(YeastGene2, HumanGene2), hasHomolog(HumanGene2, OtherModelOrganismGene2), hasHomolog(YeastGene2, OtherModelOrganismGene2), hasProteinDomain(HumanGene1, TargetDomain), hasProteinDomain(OtherModelOrganismGene1, TargetDomain),  
    57 hasInteractorFromDB(OtherModelOrganismGene1, OtherModelOrganismGene2)), \+ hasInteractorFromDB(HumanGene1, HumanGene2). 
     56      probableNovelInteractors(HumanGene1, HumanGene2) :- hasHomolog(HumanGene1, YeastGene1), hasInteractorFromDB(YeastGene1, YeastGene2), hasHomolog(YeastGene2, HumanGene2), hasHomolog(HumanGene2, OtherModelOrganismGene2), hasHomolog(YeastGene2, OtherModelOrganismGene2), hasProteinDomain(HumanGene1, TargetDomain), hasProteinDomain(OtherModelOrganismGene1, TargetDomain), hasInteractorFromDB(OtherModelOrganismGene1, OtherModelOrganismGene2)), \+ hasInteractorFromDB(HumanGene1, HumanGene2). 
    5857 
    5958      probableNovelInteractors(ing1, CandidateInteractor).