| | 1 | == Prospective Queries == |
| | 2 | |
| | 3 | We would like to implement an advanced search engine -- something like a Wolfram Alpha for biology. |
| | 4 | |
| | 5 | Expected queries: |
| | 6 | * Gene ID |
| | 7 | * Technical terms |
| | 8 | * Phrase search (e.g. ortholog genes of gene A) |
| | 9 | * DNA or protein sequence |
| | 10 | * : |
| | 11 | |
| | 12 | From [http://ir.ohsu.edu/genomics/2007protocol.html TREC Genomics Trac]: |
| | 13 | |
| | 14 | * <T1>What [ANTIBODIES] have been used to detect protein TLR4? |
| | 15 | * <T2>What [BIOLOGICAL SUBSTANCES] have been used to measure toxicity in response to cytarabine? |
| | 16 | * <T3>What [CELL OR TISSUE TYPES] express members of the mammalian TIM gene family? |
| | 17 | * <T4>What [DISEASES] are associated with lysosomal abnormalities in the nervous system? |
| | 18 | * <T5>What [DRUGS] have been tested in mouse models of Alzheimer's disease? |
| | 19 | * <T6>What centrosomal [GENES] are implicated in diseases of brain development? |
| | 20 | * <T7>What [MOLECULAR FUNCTIONS] does helicase protein NS3 play in HCV (Hepatitis C virus)? |
| | 21 | * <T8>What [MUTATIONS] in apolipoprotein genes are associated with disease? |
| | 22 | * <T9>Which [PATHWAYS] are possibly involved in the disease ADPKD? |
| | 23 | * <T10>What [PROTEINS] does epsin1 interact with during endocytosis? |
| | 24 | * <T11>What Streptococcus pneumoniae [STRAINS] are resistent to penicillin and erythromycin? |
| | 25 | * <T12>What [SIGNS OR SYMPTOMS] of anxiety disorder are related to lipid levels? |
| | 26 | * <T13>What [TOXICITIES] are associated with cytarabine? |
| | 27 | * <T14>What [TUMOR TYPES] are associated with Rb1 mutations? |
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| | 29 | From [http://www.flymine.org/release-20.0/templates.do FlyMine Templates]: |
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| | 31 | From participants: |
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| | 33 | * Q: I have a set of predicted genes from a newly sequenced genome of a Theileria species. What is a unique characteristic of this set from the view point of the biological pathway? Is it natural that this organism lacks thiolase in the mevalonate pathway? (Toshiaki Katayama) |
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