Changes between Version 12 and Version 13 of UseCases

Timestamp:

2010/02/09 15:00:05 (15 years ago)

Author:

gordonp

Comment:

--

UseCases

@@ -45 +45 @@
     * convert PDB relational to Sparql (kinjo-san, Francois)
     * miRbase (raoul)
+  * formulation of SPARQL queries -> RDFscape
+    * can be GUI.
   * Paul (biological hypothesis formulation)
     * predict PPI using homologs (PPI in yeast -> homolog in human) see [http://www.biomedcentral.com/1471-2164/9/426]
@@ -50 +52 @@
 [[Image(http://www.biomedcentral.com/content/figures/1471-2164-9-426-1.jpg)]]
 
-  * formulation of SPARQL queries -> RDFscape
-    * can be GUI.
+    * The query in Prolog would be something like:
+
+      probableInteractors(HumanGene1, HumanGene2) :- hasHomolog(HumanGene1, YeastGene1), hasInteractorFromDB(YeastGene1, YeastGene2), hasHomolog(YeastGene2, HumanGene2), hasHomolog(HumanGene2, OtherModelOrganismGene2), hasProteinDomain(HumanGene1, TargetDomain), hasProteinDomain(OtherModelOrganismGene1, TargetDomain), hasInteractorFromDB(OtherModelOrganismGene1, OtherModelOrganismGene2)).
+
+      probableInteractors(ing1, CandidateInteractor).
+
+      CandidateInteractor = p38MAPK ? ;
+      CandidateInteractor = MEKK4 ? ;
+
+    * Now we just need the predicates to exists in various SPARQL endpoints to give use the RDF Facts with predicates corresponding to hasHomolog, hasInteractorFromDB, and hasProteinDomain  Plus decide which way to express queries in SPARQL than span multiple services. :-)
+ 
+