Changes between Initial Version and Version 1 of Queries

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Timestamp:
2009/11/06 13:52:07 (11 years ago)
Author:
ktym
Comment:

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  • Queries

    v1 v1  
     1== Prospective Queries == 
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     3We would like to implement an advanced search engine -- something like a Wolfram Alpha for biology.  
     4 
     5Expected queries: 
     6 * Gene ID 
     7 * Technical terms 
     8 * Phrase search (e.g. ortholog genes of gene A) 
     9 * DNA or protein sequence 
     10 *  : 
     11 
     12From [http://ir.ohsu.edu/genomics/2007protocol.html TREC Genomics Trac]: 
     13 
     14 * <T1>What [ANTIBODIES] have been used to detect protein TLR4? 
     15 * <T2>What [BIOLOGICAL SUBSTANCES] have been used to measure toxicity in response to cytarabine? 
     16 * <T3>What [CELL OR TISSUE TYPES] express members of the mammalian TIM gene family? 
     17 * <T4>What [DISEASES] are associated with lysosomal abnormalities in the nervous system? 
     18 * <T5>What [DRUGS] have been tested in mouse models of Alzheimer's disease? 
     19 * <T6>What centrosomal [GENES] are implicated in diseases of brain development? 
     20 * <T7>What [MOLECULAR FUNCTIONS] does helicase protein NS3 play in HCV (Hepatitis C virus)? 
     21 * <T8>What [MUTATIONS] in apolipoprotein genes are associated with disease? 
     22 * <T9>Which [PATHWAYS] are possibly involved in the disease ADPKD? 
     23 * <T10>What [PROTEINS] does epsin1 interact with during endocytosis? 
     24 * <T11>What Streptococcus pneumoniae [STRAINS] are resistent to penicillin and erythromycin? 
     25 * <T12>What [SIGNS OR SYMPTOMS] of anxiety disorder are related to lipid levels? 
     26 * <T13>What [TOXICITIES] are associated with cytarabine? 
     27 * <T14>What [TUMOR TYPES] are associated with Rb1 mutations? 
     28 
     29From [http://www.flymine.org/release-20.0/templates.do FlyMine Templates]: 
     30 
     31From participants: 
     32 
     33 * Q: I have a set of predicted genes from a newly sequenced genome of a Theileria species. What is a unique characteristic of this set from the view point of the biological pathway? Is it natural that this organism lacks thiolase in the mevalonate pathway? (Toshiaki Katayama) 
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