Changes between Version 3 and Version 4 of Queries

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Timestamp:
2009/11/06 13:59:46 (7 years ago)
Author:
ktym
Comment:

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  • Queries

    v3 v4  
    3030 
    3131 * Disease [Human] --> Genes + D. melanogaster homologues (filter on BLAST E-Value). 
    32  ** For a specified human disease, show all associated human genes and their Drosophila homologues as identified with BLAST. Results are filtered by a specified E-Value, the lower the E-Value, the better the match. (Data Source: Homophila). 
     32   * For a specified human disease, show all associated human genes and their Drosophila homologues as identified with BLAST. Results are filtered by a specified E-Value, the lower the E-Value, the better the match. (Data Source: Homophila). 
    3333 
    3434 * EST clone [A. gambiae] --> Chromosomal location + Gene + D. melanogaster orthologue + Pathway. 
    35  ** For a particular A. gambiae EST clone, show its chromosomal location, the corresponding A. gambiae gene, the D. melanogaster orthologue and the pathway. (Data Source: VectorBase, InParanoid, KEGG, Reactome, FlyReactome). 
     35   * For a particular A. gambiae EST clone, show its chromosomal location, the corresponding A. gambiae gene, the D. melanogaster orthologue and the pathway. (Data Source: VectorBase, InParanoid, KEGG, Reactome, FlyReactome). 
    3636 
    3737 
     
    4040 * Q: I have a set of predicted genes from a newly sequenced genome of a Theileria species. What is a unique characteristic of this set from the view point of the biological pathway? Is it natural that this organism lacks thiolase in the mevalonate pathway? (Toshiaki Katayama) 
    4141 
    42 To resolve this sample question, we need taxonomically classified list of biological modules in the pathway filled with a phylogenetic profile of orthologous genes among related species. Then we can confirm its absence with protein2genome mapping, predicted sub cellular localization of the enzyme, knowledge on reaction in the organelle (apicoplast) from related journal articles and reviews. Most of components are already in databases but none of them are semantically linked with each other. 
     42   * To resolve this sample question, we need taxonomically classified list of biological modules in the pathway filled with a phylogenetic profile of orthologous genes among related species. Then we can confirm its absence with protein2genome mapping, predicted sub cellular localization of the enzyme, knowledge on reaction in the organelle (apicoplast) from related journal articles and reviews. Most of components are already in databases but none of them are semantically linked with each other. 
    4343 
    4444